|
KMID : 0895820220320010107
|
|
Journal of Oriental Rehabilitation Medicine
2022 Volume.32 No. 1 p.107 ~ p.124
|
|
|
Optimal Combination of Acupoints Based on Network Analysis for Chemotherapy-Induced Peripheral Neuropathy
|
|
Kim Min-Woo
Kim Joong-Il
Lee Jin-Hyun
Jo Dong-Chan
Kang Su-Bin
Lee Ji-Won
Lee Ji-Won
Park Tae-Yong
Ko Youn-Seok
|
|
|
Abstract
|
|
|
Objectives This study aimed to identify optimal combinations of acupoints used to treat chemotherapy-induced peripheral neuropathy (CIPN).
Methods We searched four international databases (MEDLINE, EMBASE, the Allied and Complementary Medicine Databases [AMED], and China National Knowledge Infrastructure [CNKI]) and five Korean databases (DBpia, Research Information Sharing Service [RISS], Korean Studies Information Service System [KISS], Oriental Medicine Advanced Searching Integrated System [OASIS], and KoreaMed) to identify randomized controlled trials (RCTs) that used acupuncture to treat CIPN. Network analysis was performed on the acupoints used in more than three included articles. We constructed a network by calculating the Jaccard similarity coefficient between acupoints and applied minimum spanning tree. Then, modularity analysis, degree centrality (Cd), and betweenness centrality (Cb) were used to analyze properties of the acupoints.
Results A total of 25 articles were included. 24 acupoints were extracted from 25 articles.
The combinations of acupoints having the highest Jaccard similarity coefficient were {EX-UE9, EX-LE10} and {ST36, SP6}. In the modularity analysis, acupoints were classified to six modules. ST40, EX-UE11, and KI6 had the highest Cd value while ST40, GB34 had the highest Cb value.
Conclusions This study found the systematic framework of acupoint combinations used in CIPN studies. This study is expected to provide new perspectives of CIPN treatment to therapists. A RCT is in progress of using the network of this study as a guideline. If significant results are derived from the RCT, it will be possible to lay the groundwork to consider acupuncture for CIPN treatment.
|
|
|
KEYWORD
|
|
|
Chemotherapy-induced peripheral neuropathy, Social network analysis, Acupuncture
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|